Member Publications

  • Peer-Reviewed Publications from Members of the RNAi Global Initiative

    • Click a year to view those publications: 

    • 2011 

    • 2010 

    • 2009 

    • 2008 

    • 2007 

       

       

    2011

    Keklikoglou I, et al. (2011) MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways. Oncogene. 2011 Dec 12. doi: 10.1038/onc.2011.571. [Epub ahead of print] Pubmed 

    Jailkhani N, et al. (2011) Delineation of key regulatory elements identifies points of vulnerability in the mitogen-activated signaling network. Genome Res. 2011 Aug 24. [Epub ahead of print] Pubmed  

    Chong R, et al. (2011) RNAi Screen Reveals Host Cell Kinases Specifically Involved in Listeria monocytogenes Spread from Cell to Cell. PLoS One. 2011;6(8):e23399. Epub 2011 Aug 10. Pubmed  

    Bai SW, et al. (2011) Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. BMC Biol. 2011 Aug 11;9(1):54. Pubmed  

    Genovesio A, et al. (2011) Automated Genome-Wide Visual Profiling of Cellular Proteins Involved in HIV Infection. J Biomol Screen. 2011 Aug 12. [Epub ahead of print] PubMed  

    Zhang JD, et al. (2011) Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation. PLoS One. 2011;6(7):e22176. Epub 2011 Jul 13. Pubmed  

    Genovesio A, et al. (2011) Visual genome-wide RNAi screening to identify human host factors required for Trypanosoma cruzi infection. PLoS One. 2011;6(5):e19733. Epub 2011 May 20. PubMed  

    Jiang M, et al. (2011) Tales from an academic RNAi screening facility; FAQs. Brief Funct Genomics. Jul;10(4):227-37. doi: 10.1093/bfgp/elr016. Epub 2011 Apr 28. PubMed  

    Nijwening JH, et al. (2011) Screening for modulators of cisplatin sensitivity: Unbiased screens reveal common themes. Cell Cycle. Feb 1;10(3): 380-6. Epub 2011 Feb 1. PubMed 

    2010

    Samavarchi-Tehrani P, et al (2010) Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell Jul 2;7(1):64-77. PubMed 

     

    Lipinski MM, et al. (2010) A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions. Dev Cell 18, 1041-05220627085. PubMed 

     

    Cappell KM, et al. (2010) Symplekin specifies mitotic fidelity by supporting microtubule dynamics. Mol Cell Biol. 2010 Nov;30(21):5135-44. Epub 2010 Sep 7. PubMed 

     

    Whitehurst AW, et al. (2010) Tumor antigen acrosin binding protein normalizes mitotic spindle function to promote cancer cell proliferation. Cancer Res. 2010 Oct 1;70(19):7652-61. Epub 2010 Sep 28. PubMed 

     

    Juul N, et al. (2010) Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials. Lancet Oncol. 2010 Apr;11(4):358-65. Epub 2010 Feb 26. PubMed 

     

    Smith JA, et al. (2010) Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. PNAS 107(8):3752-7. PubMed 

     

    Tolopko AN, et al. (2010) Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities. BMC Bioinformatics 11(1): 260. PubMed  

     

    Leber B, et al. (2010) Proteins Required for Centrosome Clustering in Cancer Cells. Science Translational Medicine, 2: 33ra38. PubMed  

     

    Fuchs, F et al. (2010) Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. Mol Syst Biol. 2010 Jun 8;6:370 PubMed  

     

    Santhakumar, D et al. (2010) Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs. Proc Natl Acad Sci U S A. Aug 3;107(31):13830-5 PubMed 

     

    Komurov, K et al. (2010) Comprehensive Mapping of the Human Kinome to Epidermal Growth Factor Receptor Signaling. J Biol Chem. Jul 2;285(27):21134-42 PubMed  

     

    Burrows, AE et al. (2010) Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence. Proc Natl Acad Sci U S A. Aug 10;107(32):14280-5 PubMed-  

    Nakada, S et al. (2010) Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature. Aug 19;466(7309):941-6 PubMed  

     

    Ahmed AA, et al. (2010) SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer. Cancer Cell. Aug 9;18(2):109-21 PubMed  

    2009

    Jrgensen C, et al (2009) Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells. Science Dec 11;326:1502-9. PubMed 

     

    Miller BW,et al. (2009) Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway. Molecular Systems Biology 5:315. PubMed 

     

    Brass, A.L, et al. (2009). The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus. Cell 139:1243-1254. PubMed 

     

    Hu, G., et al. (2009) A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal. Genes Dev. 2009 Apr 1:23(7):837-48. PubMed 

     

    Li, Q., et al. (2009). A genome genetic screen for host factors required for hepatitis C virus propagation. PNAS 106(38):16410-5. PubMed 

     

    Tai, A.W., et al. (2009). A functional genomic screen identifies cellular cofactors of Hepatitis C virus replication. Cell Host Microbe. 2009 Mar 19;5(3):298-307. PubMed 

     

    Tsui, M., et al. (2009). An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor. PLoS One. 2009 Oct. 5;4(10):e7339. PubMed 

     

    Birmingham A, et al. (2009) Statistical methods for analysis of high-throughput RNA interference screens. Nat Methods. Aug;6(8):569-75. PubMed 

     

    Stewart GS, et al. (2009) The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell. 136(3):420-34. PubMed 

    2008

    Lau KS, et al. (2008) Genome-scale identification of UDP-GlcNAc-dependent pathways. Proteomics. 8(16):3294-302. PubMed 

     

    Ohn, T. et al. (2008) A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nature Cell Biology 10(10): 1224-1231. PubMed 

     

    Brass, A.L. et al. (2008) Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen. Science 319, 921-926. PubMed 

     

    Krishnan, M.N. et al. (2008) RNA interference screen for human genes associated with West Nile virus infection. Nature. 455 (7210):242-245.. PubMed 

     

    Tang, W. et al. (2008) A genome-wide RNAi screen for Wnt/β-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. PNAS 105: 9697-9702. PubMed  

     

    Simpson K, et al (2008) Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nature Cell Biology 10(9): 1027-1038. PubMed  

    2007

    Kolas, N. K. et al. (2007) Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase. Science, 318: 1637 - 1640. PubMed 

     

    Swanton C, et al. (2007) Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to Paclitaxel and other chemotherapeutic drugs. Cancer Cell. 2007 Jun;11(6):498-512. PubMed 

     

    Whitehurst AW, et al. (2007) Synthetic lethal screen identification of chemosensitizer loci in cancer cells. Nature. 2007 Apr 12;446(7137):815-9. PubMed