The aim of CIMR is to provide a unique interface between basic and clinical science that underpins our major goal of determining and understanding the molecular mechanisms of disease. CIMR supports excellent basic research and encourages collaborations between research groups and across major research themes, which broadly encompass medical genetics, metabolic medicine, cell biology, immunology, developmental biology and structural biology.
All of the scientists in CIMR are members of 'home' Departments of the University of Cambridge. At present there are 6 groups at CIMR who will be taking part in the RNAi Global Initiative. Four of the groups are led by basic cell biologists: Margaret Robinson, Paul Luzio (who is also the Director of CIMR), Matthew Seaman, and Folma Buss. The other two groups are led by clinicians: Paul Lehner and David Rubinsztein.
We all have an interest in membrane traffic, and we are looking forward to screening the human genome library to try to find new players in the particular pathways we work on, and then to determine their role in both health and disease. We will be sharing the library with Ashok Venkitaraman and his colleagues at our neighbouring institute, the Hutchison/MRC Centre, who will be using the library to address questions relating to chromosomal instability and cancer. For more information on CIMR, visit our website at http://www.cimr.cam.ac.uk
RNAi Global Principal Investigators:
Margaret Robinson
Paul Luzio
Matthew Seaman
Folma Buss
Paul Lehner
David Rubinsztein |
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The Hutchison/MRC Research Centre at the University of Cambridge aims to exploit recent advances in the understanding of cancer for the benefit of cancer patients.
The Institute houses the Medical Research Council's Cancer Cell Unit and research groups from the Cancer Research UK Department of Oncology, with a total of about 150 researchers in 15 research groups.
On-going research builds bridges from the cell biology and genetics of cancer towards the prevention, diagnosis and treatment of cancer in the clinic. Further information is available at www.hutchison-mrc.cam.ac.uk
RNAi Global Principal Investigator:
Ashok Venkitaraman |
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