Peer-reviewed Publications from Members of the RNAi Global Initiative

2010

Smith JA, et al. (2010) Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression. PNAS 107(8):3752-7. PubMed

Tolopko AN, et al. (2010) Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities. BMC Bioinformatics 11(1): 260. PubMed

Leber B, et al. (2010) Proteins Required for Centrosome Clustering in Cancer Cells. Science Translational Medicine, 2: 33ra38. PubMed

2009

Brass, A.L, et al. (2009). The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus. Cell 139:1243-1254. PubMed

Hu, G., et al. (2009) A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal. Genes Dev. 2009 Apr 1:23(7):837-48. PubMed

Li, Q., et al. (2009). A genome genetic screen for host factors required for hepatitis C virus propagation. PNAS 106(38):16410-5. PubMed

Tai, A.W., et al. (2009). A functional genomic screen identifies cellular cofactors of Hepatitis C virus replication. Cell Host Microbe. 2009 Mar 19;5(3):298-307. PubMed

Tsui, M., et al. (2009). An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor. PLoS One. 2009 Oct. 5;4(10):e7339. PubMed

Birmingham A, et al. (2009) Statistical methods for analysis of high-throughput RNA interference screens. Nat Methods. Aug;6(8):569-75. PubMed

Stewart GS, et al. (2009) The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell. 136(3):420-34. PubMed

2008

Lau KS, et al. (2008) Genome-scale identification of UDP-GlcNAc-dependent pathways. Proteomics. 8(16):3294-302. PubMed

Ohn, T. et al. (2008) A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nature Cell Biology 10(10): 1224-1231. PubMed

Brass, A.L. et al. (2008) Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen. Science 319, 921-926. PubMed

Krishnan, M.N. et al. (2008) RNA interference screen for human genes associated with West Nile virus infection. Nature. 455 (7210):242-245.. PubMed

Tang, W. et al. (2008) A genome-wide RNAi screen for Wnt/β-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. PNAS 105: 9697-9702. PubMed

Simpson K, et al (2008) Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nature Cell Biology 10(9): 1027-1038. PubMed

2007

Kolas, N. K. et al. (2007) Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase. Science, 318: 1637 - 1640. PubMed

Swanton C, et al. (2007) Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to Paclitaxel and other chemotherapeutic drugs. Cancer Cell. 2007 Jun;11(6):498-512. PubMed