![]() |
| HOME MEMBER LOGIN ABOUT US CONTACT MEMBER LIST |
| Vrije University Medical Center (VUMC) | ||||
| Thomas Wurdinger | ||||
Thomas Wurdinger, PhD, received his MSc degree at the VU University in 2001. In 2005 he received his PhD at the Virology division of Utrecht University in collaboration with the Gene Therapy division of the VU University Medical Center, for which he received the Greiner Award from the Dutch Society of Gene Therapy. In 2005 he started working as a postdoctoral fellow at the Molecular Neurogenetics Unit and the Center of Molecular Imaging Research of the Massachusetts General Hospital and Harvard Medical School, where he started working on brain tumor miRNAs and molecular imaging techniques, and where he received an American Brain Tumor Association Fellowship Award. Since December 2007 he is heading the lab of the Neuro-oncology Research Group at the VUmc Cancer Center Amsterdam. His main research focus is on the identification of system therapeutics for the treatment of brain tumors. This includes exploiting large-scale siRNA library screening to determine factors that contribute to brain tumor growth and migration. Selected PublicationsWurdinger, T., Badr, C., Pike, L., Breakefield, X.O., and Tannous, B.A. A secreted luciferase for ex vivo monitoring of in vivo processes. Nat. Methods. 2008; 5(2):171-3. Nahrendorf, M., Swirski, F. K., Aikawa, E., Stangenberg, L., Wurdinger, T., Figueiredo, J. L., Weissleder, R., Pittet, M. J.: The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J. Exp. Med. 2007; 204(12):3037-47. Mack, G. (commentary Wurdinger, T.) MicroRNA gets down to business. Nat. Biotech. 2007; 25(6):631-38. Wurdinger, T. and Costa, F. F.: Molecular therapy in the microRNA era. Pharmacogenomics J. 2006; 7(5):297-304. Wurdinger, T., Verheije, M. H., van der Aa, L., Bosch, B. J., de Haan, C. A., van Beusechem, V. W., Gerritsen, W. R., Rottier, P. J.: Antibody-mediated targeting of viral vectors to the Fc receptor expressed on acute myeloid leukemia cells. Leukemia, 2006; 20(12):2182-4. Wurdinger, T., Verheije, M. H., Broen, K., Bosch, B. J., Haijema, B. J., de Haan, C. A., van Beusechem, V. W., Gerritsen, W. R., Rottier, P. J. Soluble receptor-mediated targeting of mouse hepatitis coronavirus to the human epidermal growth factor receptor. J Virol. 2005 Dec; 79(24):15314-22. Wurdinger, T., Verheije, M. H., Raaben, M., Bosch, B. J., de Haan, C. A., van Beusechem, V. W., Rottier, P. J., Gerritsen, W. R. Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody. Gene Ther. 2005; 12(18):1394-404. van Beusechem, V. W., Mastenbroek, D. C. van den Doel, P. B., Lamfers, M., Grill, J., Wurdinger, T., Haisma, H. J., Pinedo, H. M., Gerritsen, W. R. Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors. Gene Ther. 2003; 10: 1982-1991. Contact DetailsThomas Wurdinger, Ph.D. Dept. Neurosurgery, Neuro-ocology Research Group (NRG) Identification of genes involved in brain tumor systems. Back to VUMC |
||||
|
Home | Member Login | About Us | Contact | Member List © 2005-2006 Genome-Wide RNAi Global Initiative |