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| Vrije University Medical Center (VUMC) |
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The VU Medical Center (VUmc) has been known by this name since January 2001, when the Academic Hospital and the Faculty of Medicine of the Vrije Universiteit Amsterdam were integrated. As an academic center, the VUmc is specialized in helping patients with uncommon clinical pictures and those who require highly intensive and complex care. The VUmc offers tertiary clinical care and referral-center care in certain areas. This often involves unique diagnosis and treatment, and specialized research. The VUmc contributes to the maintenance and improvement of public health by conducting research, disseminating new knowledge, and by educating a new generation of care providers. The scientific research at VUmc is based on five pivotal points, which are embodied by multidisciplinary research institutes. Research in the area of cancer and immunology is organized in the VUmc Institute for Cancer and Immunology (V-ICI). V-ICI participates in two research and graduate schools accredited by the Royal Netherlands Academy of Arts and Sciences, i.e., the Oncology Graduate School Amsterdam and the Amsterdam-Leiden Institute for Immunology.
The VUmc Cancer Center Amsterdam (CCA) is the cancer expertise center of the VUmc. The CCA aims to provide the best possible care and treatment to patients with cancer. To this end, the CCA integrates and strengthens oncology expertise at the VUmc, stimulating translation of basic research programs into clinical useful tools and methods. In 2006, CCA and V-ICI merged and opened a new research building where most basic and translational oncology research being conducted at VUmc is clustered. In addition, it was decided to complement existing core facilities for microarray and proteomics research by establishing a core facility for RNAi library screening. This RNA Interference Functional Oncogenomics Laboratory (RIFOL) was set up with financial support from the Foundation SBGO, one of the foundations supporting CCA/V-ICI. The RIFOL serves a wide range of labs at VUmc and represents VUmc as member of the RNAi Global Initiative.
For further information, visit our website at
http://www.vumc.nl/. |
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VU Medical Center
VUmc Cancer Center Amsterdam
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RNAi Global Principal Investigators:
Victor W. van Beusechem, Ph.D.
Dept. Medical Oncology, Gene Therapy Group/RIFOL
Identification of genes involved in oncolytic virus
replication in cancer cells.
Web
Email
Frank A.E. Kruyt, Ph.D.
Dept. Medical Oncology, Apoptosis Group
Dissecting apoptotic pathways in cancer, in particular
non-small cell lung cancer, for the development and
design of improved therapeutic strategies. Identification
of key apoptotic targets in NSCLC by RNAi library screening.
Web
Email
Gerrit A. Meijer, MD Ph.D.
Dept. Pathology, Tumor Profiling Unit
Identification of genes that drive colon adenoma-to-carcinoma
progression.
Web
Email
Renske D.M. Steenbergen, Ph.D.
Dept. Pathology, Molecular Pathology Unit
Elucidation of human papillomavirus (HPV)-mediated
carcinogenesis of the uterine cervix and translation
of this basic knowledge into novel approaches for prevention
and treatment of cervical cancer.
Email
Ruud H. Brakenhoff, Ph.D.
Dept. Otolaryngology/Head and Neck Surgery
Identification of genes involved in HNSCC carcinogenesis and genes
modulating chemoradiation resistance in head and neck cancer
Email
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Jacqueline Cloos, Ph.D.
Dept. Pediatric Oncology/Hematology
Find new treatment targets in relevant signal
transduction pathways for innovative therapy
of leukemia.
Web1, Web2
Email
Johan de Winter, Ph.D.
Dept. Clinical Genetics
Chromosomal instability and cancer, with a
focus on inherited cancer predisposition
syndromes.
Email
Teunis B.H. Geijtenbeek, Ph.D.
Dept. Molecular Cell Biology and Immunology
Defining molecular mechanisms of immune
subversion by pathogens and tumors.
Email
Thomas Wurdinger, Ph.D.
Dept. Neurosurgery, Neuro-ocology Research
Group (NRG)
Identification of genes involved in
brain tumor systems.
Email
Primary Contact Information:
Victor W. van Beusechem, Ph.D.
RNAi Functional Oncogenomics Laboratory
Department of Medical Oncology
Phone: +31.20.444.2162
Fax: +31.20.444.2126
Web
Email
Institutional Contact:
Ans Buijs and Joke van Diemen
Office of the Director Dr. W.R. Gerritsen
VUmc CCA / V-ICI
Phone: +31 20 4444 342 or +31 20 4444 356
Fax: +31 20 4444 081
Email
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