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Vrije University Medical Center (VUMC)
 
The VU Medical Center (VUmc) has been known by this name since January 2001, when the Academic Hospital and the Faculty of Medicine of the Vrije Universiteit Amsterdam were integrated. As an academic center, the VUmc is specialized in helping patients with uncommon clinical pictures and those who require highly intensive and complex care. The VUmc offers tertiary clinical care and referral-center care in certain areas. This often involves unique diagnosis and treatment, and specialized research. The VUmc contributes to the maintenance and improvement of public health by conducting research, disseminating new knowledge, and by educating a new generation of care providers. The scientific research at VUmc is based on five pivotal points, which are embodied by multidisciplinary research institutes. Research in the area of cancer and immunology is organized in the VUmc Institute for Cancer and Immunology (V-ICI). V-ICI participates in two research and graduate schools accredited by the Royal Netherlands Academy of Arts and Sciences, i.e., the Oncology Graduate School Amsterdam and the Amsterdam-Leiden Institute for Immunology.

The VUmc Cancer Center Amsterdam (CCA) is the cancer expertise center of the VUmc. The CCA aims to provide the best possible care and treatment to patients with cancer. To this end, the CCA integrates and strengthens oncology expertise at the VUmc, stimulating translation of basic research programs into clinical useful tools and methods. In 2006, CCA and V-ICI merged and opened a new research building where most basic and translational oncology research being conducted at VUmc is clustered. In addition, it was decided to complement existing core facilities for microarray and proteomics research by establishing a core facility for RNAi library screening. This RNA Interference Functional Oncogenomics Laboratory (RIFOL) was set up with financial support from the Foundation SBGO, one of the foundations supporting CCA/V-ICI. The RIFOL serves a wide range of labs at VUmc and represents VUmc as member of the RNAi Global Initiative.

For further information, visit our website at
http://www.vumc.nl/.
 
VUMC Medical Center
VU Medical Center

VUMC Cancer Center
VUmc Cancer Center Amsterdam

 
 

RNAi Global Principal Investigators:

    Victor W. van Beusechem, Ph.D.
    Dept. Medical Oncology, Gene Therapy Group/RIFOL
    Identification of genes involved in oncolytic virus
      replication in cancer cells.

    Web
    Email


    Frank A.E. Kruyt, Ph.D.
    Dept. Medical Oncology, Apoptosis Group
    Dissecting apoptotic pathways in cancer, in particular
     non-small cell lung cancer, for the development and
     design of improved therapeutic strategies. Identification
     of key apoptotic targets in NSCLC by RNAi library screening.

    Web
    Email


    Gerrit A. Meijer, MD Ph.D.
    Dept. Pathology, Tumor Profiling Unit
    Identification of genes that drive colon adenoma-to-carcinoma
     progression.

    Web
    Email


    Renske D.M. Steenbergen, Ph.D.
    Dept. Pathology, Molecular Pathology Unit
    Elucidation of human papillomavirus (HPV)-mediated
     carcinogenesis of the uterine cervix and translation
     of this basic knowledge into novel approaches for prevention
     and treatment of cervical cancer.

    Email

    Ruud H. Brakenhoff, Ph.D.
    Dept. Otolaryngology/Head and Neck Surgery
    Identification of genes involved in HNSCC carcinogenesis and genes
       modulating chemoradiation resistance in head and neck cancer

    Email

 

    Jacqueline Cloos, Ph.D.
    Dept. Pediatric Oncology/Hematology
    Find new treatment targets in relevant signal
       transduction pathways for innovative therapy
       of leukemia.

    Web1Web2
    Email


    Johan de Winter, Ph.D.
    Dept. Clinical Genetics
    Chromosomal instability and cancer, with a
       focus on inherited cancer predisposition
       syndromes.

    Email

    Teunis B.H. Geijtenbeek, Ph.D.
    Dept. Molecular Cell Biology and Immunology
    Defining molecular mechanisms of immune
       subversion by pathogens and tumors.

    Email

    Thomas Wurdinger, Ph.D.
    Dept. Neurosurgery, Neuro-ocology Research
    Group (NRG)
    Identification of genes involved in
       brain tumor systems.

   Email

Primary Contact Information:
    Victor W. van Beusechem, Ph.D.
    RNAi Functional Oncogenomics Laboratory
    Department of Medical Oncology
    Phone: +31.20.444.2162
    Fax: +31.20.444.2126
    Web
    Email


Institutional Contact:
    Ans Buijs and Joke van Diemen
    Office of the Director Dr. W.R. Gerritsen
    VUmc CCA / V-ICI
    Phone: +31 20 4444 342 or +31 20 4444 356
    Fax: +31 20 4444 081
   Email
 
 



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